Free Research Resource from the Mitton Lab: MAPs OF RNA-POLYMERASE-II BINDING AROUND GENE TRANSCRIPTION START SITES IN MATURING PHOTORECEPTORS.

With some computer savvy, and biochemistry knowledge, there are ways to detect genes activated in maturing photoreceptors in vivo, that are not detected by DNA micro-arrays or the average RNA-Seq method. While the general expectation was that photoreceptors need to be isolated, Dr Mitton used an alternative approach to leave rod-photoreceptors where they are, in the retina. Continue reading