With some computer savvy, and biochemistry knowledge, there are ways to detect genes activated in maturing photoreceptors in vivo, that are not detected by DNA micro-arrays or the average RNA-Seq method. While the general expectation was that photoreceptors need to be isolated, Dr Mitton used an alternative approach to leave rod-photoreceptors where they are, in the retina. Continue reading
Free Research Resource from the Mitton Lab: MAPs OF RNA-POLYMERASE-II BINDING AROUND GENE TRANSCRIPTION START SITES IN MATURING PHOTORECEPTORS.
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